Japanese spotted fever: report of 31 cases and review of the literature.
Japanese spotted fever: report of 31 cases and review of the literature.
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DOI：
10.3201/eid0302.970203
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发表时间：
1997-04
影响因子：
11.8
通讯作者：
Mahara, F
中科院分区：
文献类型：
--
作者：
Mahara, F
斑点热群（SFG）立克次体病，由蜱传播，长期以来被认为在日本不存在。1984年首次报道了3例日本斑点热（JSF）临床病例。病原体被分离并命名为日本立克次体。到1996年10月，德岛县有31例确诊为JSF。感染的患者通常有急性高热、头痛和特征性皮肤病; 90%的患者观察到焦痂。在发现JSF后，日本西南部和中部报告了一百多例病例。最近的调查显示蜱虫是最有可能的传播媒介。作为一种新出现的传染病，JSF通常不被临床医生认识;因此，即使它没有造成致命病例，也值得仔细监测。
Spotted fever group (SFG) rickettsioses, which are transmitted by ticks, were long thought not to exist in Japan. Three clinical cases of Japanese spotted fever (JSF) were first reported in 1984. The causative agent was isolated and named Rickettsia japonica. Through October 1996, 31 cases were diagnosed as JSF in Tokushima Prefecture. Infected patients typically had acute high fever, headache, and characteristic exanthema; eschar was observed in 90%. After the discovery of JSF, more than a hundred cases were reported in southwestern and central Japan. Recent surveys show ticks to be the most probable vectors. As an emerging infectious disease, JSF is not commonly recognized by clinicians; therefore, even though it has not caused fatal cases, it merits careful monitoring.