From gene to organismal phylogeny: Reconciled trees and the gene tree species tree problem
From gene to organismal phylogeny: Reconciled trees and the gene tree species tree problem
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DOI：
10.1006/mpev.1996.0390
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发表时间：
1997-04-01
影响因子：
4.1
通讯作者：
Charleston, MA
中科院分区：
文献类型：
--
作者：
Page, RDM;Charleston, MA
基因复制、丢失和谱系分类的过程会导致基因的同源性与物种的同源性之间的不一致。这种不一致使得从前者推断后者的任务变得复杂。我们描述了使用调和树重建的历史基因树的物种树。标记的树允许基因树的历史被可视化，并且还量化两个树之间的关系。协调树的成本是协调基因树与其物种树所需的重复和基因丢失的总数。我们描述了使用启发式搜索，找到物种树，产生的调和树成本最低。该方法可用于从一个或多个基因树推断物种树。(C)北京：科学出版社.
The processes of gene duplication, loss, and lineage sorting can result in incongruence between the phylogenies of genes and those of species. This incongruence complicates the task of inferring the latter from the former. We describe the use of reconciled trees to reconstruct the history of a gene tree with respect to a species tree. Reconciled trees allow the history of the gene tree to be visualized and also quantify the relationship between the two trees. The cost of a reconciled tree is the total number of duplications and gene losses required to reconcile a gene tree with its species tree. We describe the use of heuristic searches to find the species tree which yields the reconciled tree with the lowest cost. This method can be used to infer species trees from one or more gene trees. (C) 1997 Academic Press.