In vitro comparison of the charge-injection limits of activated iridium oxide (AIROF) and platinum-iridium microelectrodes
In vitro comparison of the charge-injection limits of activated iridium oxide (AIROF) and platinum-iridium microelectrodes
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DOI：
10.1109/tbme.2005.851503
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发表时间：
2005-09-01
影响因子：
4.6
通讯作者：
Plante, TD
中科院分区：
文献类型：
--
作者：
Cogan, SF;Troyk, PR;Plante, TD
已在体外使用刺激波形比较了具有相似几何面积和形状的活化氧化铱电极（AIROF）和PtIr微电极的电荷注入极限，该刺激波形在脉冲间隔期间提供阴极电流脉冲，并对电极偏置电位进行限流控制。在0.1-0.7 V（相对于Ag垂直条AgCl）和20，50和100 Hz的脉冲频率的偏置范围内的电荷注入限制进行了比较。AIROF能够注入PtIr电极4至10倍的电荷，在0.7 V偏压和20 Hz频率下获得的最大值为3.9 mC/cm（2）。
The charge-injection limits of activated iridium oxide electrodes (AIROF) and PtIr microelectrodes with similar geometric area and shape have been compared in vitro using a stimulation waveform that delivers cathodal current pulses with current-limited control of the electrode bias potential in the interpulse period. Charge-injection limits were compared over a bias range of 0.1-0.7 V (versus Ag vertical bar AgCl) and pulse frequencies of 20, 50, and 100 Hz. The AIROF was capable of injecting between 4 and 10 times the charge of the PtIr electrode, with a maximum value of 3.9 mC/cm(2) obtained at a 0.7 V bias and 20 Hz frequency.