Safety of coadministration of ezetimibe and statins in patients with hypercholesterolaemia: a meta‐analysis
Safety of coadministration of ezetimibe and statins in patients with hypercholesterolaemia: a meta‐analysis
复制标题
DOI：
10.1111/imj.12706
复制
发表时间：
2015-05
影响因子：
2.1
通讯作者：
L. Luo;X. Yuan;Wenhan Huang;Feifeng Ren;H. Zhu;Yaning Zheng;Lin Tang
中科院分区：
文献类型：
--
作者：
L. Luo;X. Yuan;Wenhan Huang;Feifeng Ren;H. Zhu;Yaning Zheng;Lin Tang
高胆固醇血症是心脑血管疾病的关键危险因素，可用多种有效的降血脂药物进行治疗。他汀类药物通常单独使用或与依折麦布联合使用。联合治疗更有效，因为它的补充方法，这对血脂水平无法控制的患者有重大好处。联合治疗的广泛应用导致副作用的发生率增加，这引起了人们的关注。
Hypercholesterolaemia is a pivotal risk factor for cardiovascular and cerebrovascular disease and is treated with many effective lipid‐lowering agents. Statins are often used alone or in combination with ezetimibe. Combination therapy is more effective because of its complementary approach, which has major benefits for patients with unmanageable lipid levels. Extensive application of combination therapy has resulted in an increased incidence of side‐effects, which has raised our concern.