Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. I. The producing organism, fermentation, isolation and biological properties.

Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. I. The producing organism, fermentation, isolation and biological properties.
复制标题

DOI：
10.7164/antibiotics.41.481
复制
发表时间：
1988-04
期刊：
The Journal of antibiotics
影响因子：
--
通讯作者：
R. Wu;L. M. Yang;T. Yokoi;K. Lee
R. Wu;L. M. Yang;T. Yokoi;K. Lee
中科院分区：
其他
文献类型：
--
作者：
R. Wu;L. M. Yang;T. Yokoi;K. Lee

文献摘要

被引文献

相似文献

从内胡小单孢菌Wu， sp. nov.的土壤分离物培养液中分离到一种新的细胞毒和抗真菌抗生素neihumicin， neihumicin对KB组织培养细胞（ED50 0.94微克/毫升）具有体外细胞毒作用，对酿酒酵母ATCC 9763具有体外抗真菌活性。
A new cytotoxic and antifungal antibiotic, neihumicin, was isolated from the culture broth of a soil isolate identified as Micromonospora neihuensis Wu, sp. nov. Neihumicin shows in vitro cytotoxicity against KB tissue culture cells (ED50 0.94 micrograms/ml) as well as antifungal activity against Saccharomyces cerevisiae ATCC 9763.