Incorporating Pharmacogenomics into Health Information Technology, Electronic Health Record and Decision Support System: An Overview

Incorporating Pharmacogenomics into Health Information Technology, Electronic Health Record and Decision Support System: An Overview
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DOI:
10.1007/s10916-016-0673-4
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发表时间:
2017-02-01
影响因子:
5.3
通讯作者:
Alanazi, Abdullah
Alanazi, Abdullah
中科院分区:
医学3区
文献类型:
--
作者:
Alanazi, Abdullah

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随着信息技术在医疗保健中的应用,药物基因组学从临床走向临床的潜力越来越大。本文综述了药物基因组学(PGx)信息的现状以及通过决策支持系统(DSS)将其纳入电子健康记录(EHR)系统的尝试。PGx信息的严格审查策略,并以行动计划的形式提供背景相关的建议-剂量调整,实验室检查,而不仅仅是信息-对于根据PGx信息提出临床建议是理想的。最后,什么药物基因组学可以提供现实的预测是将药物基因组学纳入健康信息技术的另一个重要方面。
As the adoption of information technology in healthcare is rising, the potentiality of moving Pharmacogenomics from benchside to bedside is aggravated. This paper reviews the current status of Pharmacogenomics (PGx) information and the attempts for incorporating them into the Electronic Health Record (EHR) system through Decision Support Systems (DSSs). Rigorous review strategies of PGx information and providing context-relevant recommendations in form of action plan-dose adjustment, lab tests rather than just information-would be ideal for making clinical recommendations out of PGx information. Lastly, realistic projections of what pharmacogenomics can provide is another important aspect in incorporating Pharmacogenomics into health information technology.