Palladium‐Catalyzed Intramolecular Oxidative CH Sulfuration of Aryl Thiocarbamates
Palladium‐Catalyzed Intramolecular Oxidative CH Sulfuration of Aryl Thiocarbamates
复制标题
DOI：
10.1002/adsc.201400306
复制
发表时间：
2014-08
影响因子：
5.4
通讯作者：
Yingwei Zhao;Yinjun Xie;C. Xia;Hanmin Huang
中科院分区：
文献类型：
--
作者：
Yingwei Zhao;Yinjun Xie;C. Xia;Hanmin Huang
研究了钯催化的芳基硫代氨基甲酸酯分子内C-H键硫化反应。这一策略为合成具有广泛取代基耐受性的苯并[d][1，3]氧杂硫醇-2-酮化合物提供了一条新的途径。机理研究表明，C-H活化-硫化反应生成2-亚氨基-1，3-苯并氧硫杂环戊烯中间体可能涉及一个亲电钯化过程。
A palladium-catalyzed intramolecular C-H bond sulfuration reaction of aryl thiocarbamates has been developed. This strategy provides a new route to benzo[d][1,3] oxathiol-2-ones with tolerance of a wide range of substituents. Mechanistic studies suggested that the C-H activation-sulfuration to afford 2-imino-1,3-benzoxathiole intermediate might involve an electrophilic palladation process.