Quantitative analysis of continuous-wave Doppler spectral broadening for the diagnosis of carotid disease: results of a multicenter study.
Quantitative analysis of continuous-wave Doppler spectral broadening for the diagnosis of carotid disease: results of a multicenter study.
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用于诊断颈动脉疾病的连续波多普勒频谱展宽的定量分析：多中心研究的结果。
DOI：
10.1016/0741-5214(86)90386-1
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发表时间：
1986
影响因子：
4.3
通讯作者：
M. A. Poole
中科院分区：
文献类型：
--
作者：
K.Wayne Johnston;William H. Baker;Steven J. Burnham;Andrew C. Hayes;Cynthia A. Kupper;M. A. Poole
本文报告了一项多中心研究的结果，该研究将333项频率分析研究与连续波多普勒方法和血管造影进行了比较。通过受试者工作特征曲线，本研究记录了多普勒技术诊断颅外颈动脉狭窄的准确性，颈动脉狭窄直径缩小大于45%。它证实了最大峰值多普勒频率测量的准确性，此外，还表明，通过测量频谱增宽指数定量分析峰值收缩时的瞬时多普勒频谱具有诊断价值。使用曲线拟合技术计算了Likewise比率，并证明了如何同时使用峰值频率和光谱增宽指数来提高诊断的确定性。它的结论是，一个单独的病人有显着的颈动脉疾病的概率可以确定与测量的峰值频率和频谱展宽指数从连续波多普勒频谱波形。（《血管外科杂志》1986;4：493-504。）
This article reports the results of a multicenter study that compares 333 frequency analysis studies with the continuous-wave Doppler method with angiography. With receiver operating characteristic curves, the study documents the accuracy of the Doppler technique for the diagnosis of extracranial carotid arterial stenosis greater than 45% diameter reduction. It confirms the accuracy of the measurement of the maximal peak Doppler frequency and, in addition, shows that quantitative analysis of the instantaneous Doppler spectrum at peak systole by the measurement of the spectral broadening index is of diagnostic value. Likelihood ratios have been calculated with the use of curve-fitting techniques and it has been demonstrated how both the peak frequency and the spectral broadening index can be used together to improve the certainty of diagnosis. It is concluded that the probability that an individual patient has significant carotid arterial disease can be determined with the measurements of peak frequency and spectral broadening index from the continuous-wave Doppler spectral waveform. (J VASCSURG1986;4:493-504.)