Exploring the cognitive phenotype of autism:: Weak "central coherence" in parents and siblings of children with autism:: I.: Experimental tests
Exploring the cognitive phenotype of autism:: Weak "central coherence" in parents and siblings of children with autism:: I.: Experimental tests
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DOI：
10.1111/1469-7610.00723
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发表时间：
2001-03-01
影响因子：
7.6
通讯作者：
Frith, U
中科院分区：
文献类型：
--
作者：
Happé, F;Briskman, J;Frith, U
以前的双胞胎和家庭研究表明，自闭症的病因学有很强的遗传影响，并为一级亲属中更广泛的表型的概念提供了支持。本研究探讨了这种表型的一个当前的认知理论自闭症。自闭症男孩的父母和兄弟。患有阅读障碍的男孩和正常男孩进行了“中心连贯性”测试，自闭症儿童在这方面表现得异常出色，这是因为他们的信息处理偏向于部分/细节处理，而不是整体/意义处理。结果表明，自闭症男孩的父亲作为一个群体，在四个中央连贯性测试中表现出零碎的处理。这对任何其他群体来说都不是真的。这些发现提出了一种可能性，即更广泛的自闭症表型可能包括一种“认知风格”（弱中央一致性），可以赋予信息处理优势。
Previous twin and family studies have indicated that there are strong genetic influences in the etiology of autism, and provide support for the notion of a broader phenotype in first-degree relatives. The present study explored this phenotype in terms of one current cognitive theory of autism. Parents and brothers of boys with autism. boys with dyslexia, and normal boys were given tests of "central coherence", on which children with autism perform unusually well due to an information-processing bias favouring part/detail processing over processing of wholes/meaning. Results indicated that fathers of boys with autism, as a group, showed piecemeal processing across four tests of central coherence. This was not true for any other group. These findings raise the possibility that the broader autism phenotype may include a "cognitive style" (weak central coherence) that can confer information-processing advantages.