Estimation of pedigree errors in the UK dairy population using microsatellite markers and the impact on selection

Estimation of pedigree errors in the UK dairy population using microsatellite markers and the impact on selection
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DOI:
10.3168/jds.s0022-0302(02)74317-8
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发表时间:
2002-09-01
影响因子:
3.5
通讯作者:
Williams, JL
Williams, JL
中科院分区:
农林科学1区
文献类型:
--
作者:
Visscher, PM;Woolliams, JA;Williams, JL

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使用DNA标记估计了英国奶牛群中父系被错误识别的奶牛比例。对568头奶牛(来自168份牛奶样品和400份毛发样品)和96头推定的公畜(来自精液样品)进行了遗传标记基因型测定。头发样本的估计谱系错误率为8.8%,牛奶样本为13.1%,总体估计错误率为10%。这种水平的系谱误差将对后代检测的效率和奶牛预测育种值的准确性产生相对较大的影响。我们预测,考虑到这个错误率,对选择的响应损失约为2%至3%。
The proportion of cows in the UK dairy herd whose sires were misidentified was estimated using DNA markers. Genetic marker genotypes were determined on 568 cows (from 168 milk samples and 400 hair samples) and 96 putative sires (from semen samples). The estimated pedigree error rate from the hair samples was 8.8%, and from the milk samples, 13.1%, giving an overall estimate of the error rate of 10%. This level of pedigree errors will have a relatively large impact on the efficiency of progeny testing and the accuracy of cow predicted breeding values. We predict a loss of response to selection of approximately 2 to 3% given this error rate.