[Physiologic skin changes in pregnancy].
[Physiologic skin changes in pregnancy].
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DOI：
10.1016/j.lpm.2010.04.024
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Ben Osman, Amel
中科院分区：
文献类型：
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作者：
Zerouali, Aida;Zaraa, Ines;Ben Osman, Amel
妊娠期是激素、免疫、代谢和血管发生变化的时期。其中一些被认为是生理性的，但其他的是真正的疾病，特定于或不是怀孕。本研究旨在了解妊娠期的流行病学和临床生理皮肤病学变化。方法：我们提出了一项横向单中心研究。在La Rabta医院皮肤科就诊的100名孕妇进行了登记。皮肤科医生进行了系统详细的皮肤检查，以寻找生理性皮肤变化。结果：患者平均年龄29岁[20 ~ 46岁]。色素变化最明显（93%），以乳晕区色素沉着为主（77%）。75%的病例有腺体改变。在77%的孕妇中观察到血管改变。其中，牙龈充血最为常见（46%）。其他皮肤变化较少（扩张纹45%，痣改变35%，妊娠软疣10%）。讨论：怀孕期间皮肤的生理变化是很多的。我们的研究证实了这些变化的频率和可变性。色素改变是最常见的发现。
INTRODUCTION: Pregnancy is a period of hormonal, immunological, metabolic and vascular changes. Some of them are considered to be physiologic, but others are real diseases specific or not of pregnancy. The aim of our study is to present the epidemiological and clinical physiologic dermatological changes of pregnancy.METHODS: We present a transversal monocentric study. One hundred pregnant women attending the department of dermatology of the La Rabta hospital were enrolled. Systematic detailed cutaneous examination was performed by a dermatologist to look for a physiologic skin changes.RESULTS: The mean age was 29 years [20-46 years]. Pigmentary changes were the most preponderant (93%), dominated by the areolar region pigmentation (77%). The glandular changes were noted in 75% of cases. The vascular modifications were observed in 77% of pregnant women. Of these, gingival hyperemia was the most common (46%). Others cutaneous changes were less frequent (stria distensae 45%, nevi changes 35%, molluscum gravidarum 10%).DISCUSSION: The physiologic cutaneous changes during pregnancy are numerous. Our study confirms the frequency and the variability of these modifications. The pigmentary changes were the most common finding.