A note on the adaptive control of false discovery rates
A note on the adaptive control of false discovery rates
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DOI：
10.1111/j.1369-7412.2003.05527.x
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发表时间：
2004-01-01
影响因子：
5.8
通讯作者：
Black, MA
中科院分区：
文献类型：
--
作者：
Black, MA
当应用于控制错误发现率时，已显示使用固定拒绝区域进行多个假设检验优于标准固定错误率方法。在这项工作中，它表明，如果Benjamini和Hochberg的原始升压过程进行修改，行使自适应控制的错误发现率，其性能几乎是相同的固定拒绝区域的方法。此外，这两种方法的真实零假设的比例的依赖性进行了探讨，重点是在这个数量的估计所涉及的困难。
The use of a fixed rejection region for multiple hypothesis testing has been shown to outperform standard fixed error rate approaches when applied to control of the false discovery rate. In this work it is demonstrated that, if the original step-up procedure of Benjamini and Hochberg is modified to exercise adaptive control of the false discovery rate, its performance is virtually identical to that of the fixed rejection region approach. In addition, the dependence of both methods on the proportion of true null hypotheses is explored, with a focus on the difficulties that are involved in the estimation of this quantity.