Maternal depression and perceived social support as predictors of cognitive function trajectories during the first 3 years of life for preterm infants in Wisconsin

Maternal depression and perceived social support as predictors of cognitive function trajectories during the first 3 years of life for preterm infants in Wisconsin
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DOI:
10.1111/j.1365-2214.2011.01253.x
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发表时间:
2012-05-01
影响因子:
1.9
通讯作者:
Poehlmann, J.
Poehlmann, J.
中科院分区:
医学3区
文献类型:
--
作者:
McManus, B. M.;Poehlmann, J.

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背景在早产婴儿的家庭中,产后抑郁和儿童认知功能之间的联系并不是很清楚,但被认为是折衷的。本研究的目的是探讨母亲抑郁症状和领悟社会支持对儿童认知功能轨迹的预测作用。方法对威斯康星州早产儿(小于37周)进行纵向研究。这项研究包括在2002-2005年间在威斯康星州三个新生儿重症监护病房之一住院的130名婴儿,并一直跟踪到36个月大。使用流行病学研究中心抑郁量表测量母亲的抑郁症状。使用母亲支持量表测量社会支持。采用贝利婴幼儿发展量表第2版和斯坦福-比奈智力量表第5版对儿童的认知功能进行测量。女性(系数=5.14,SE=1.89)和非贫困(系数=11.26,SE=5.78)和母亲有研究生学历(系数=7.67,SE=3.37)最初与较高的认知水平相关。白人与更理想的认知轨迹有关。虽然抑郁不能预测儿童的认知轨迹,但产后9个月抑郁症状的临床升高与16个月时母亲报告的低社会支持时认知功能低下有关。结论产后抑郁症状似乎对早产儿的认知结局产生了有意义的动态影响,当考虑到感受到的社会支持的存在和时机时,这种影响超过了家庭社会人口风险。减轻与早产有关的发展风险的干预措施应包括反复评估产妇的社会支助和产后抑郁,并以社会弱势家庭为目标。
Background Among families of infants born preterm, the association between post-natal depression and children's cognitive function is not well understood, but thought to be compromised. The purpose of this study is to investigate maternal depressive symptoms and perceived social support as predictors of children's cognitive function trajectories.Methods This is a longitudinal study of a sample of infants born preterm (less than 37 weeks) in Wisconsin. This study includes 130 infants who were hospitalized in one of three Wisconsin neonatal intensive care units in 2002-2005 and followed until 36 months of age. Maternal depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Social support was measured using the Maternal Support Scale. Children's cognitive function was measured using the Bayley Scales of Infant Development, 2nd Edition, and the Stanford-Binet Intelligence Scale, 5th Edition.Results Children's cognitive function trajectories declined initially and then increased. Being female (coefficient = 5.14, SE = 1.89) and non-poor (coefficient = 11.26, SE = 5.78), and having a mother who has a graduate degree (coefficient = 7.67, SE = 3.37) was associated with higher levels of cognition initially. Being white was associated with a more optimal cognitive trajectory. Although depression did not predict children's cognitive trajectories, the presence of clinically elevated depressive symptoms at 9 months post term was associated with lower cognitive functioning at 16 months when mothers reported low social support.Conclusion Post-natal depressive symptoms appear to have a meaningful, dynamic influence on the cognitive outcomes of children born preterm, above and beyond family socio-demographic risk when the presence and timing of perceived social support are considered. Interventions to ameliorate developmental risk associated with preterm birth should include repeated assessments of maternal social support and post-natal depression and be targeted towards socially disadvantaged families.