Coalescent genealogy samplers: windows into population history.

Coalescent genealogy samplers: windows into population history.
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DOI:
10.1016/j.tree.2008.09.007
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发表时间:
2009-02
影响因子:
16.8
通讯作者:
Kuhner MK
Kuhner MK
中科院分区:
生物学1区
文献类型:
--
作者:
Kuhner MK

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基于分子数据的样本,聚合谱系取样者试图估计一个种群过去的品质,比如它的大小、生长速度、基因流动的模式或与另一个种群分化的时间。家谱抽样越来越受欢迎,因为它们有可能解开复杂的人口历史。在过去的十年中,它们被广泛应用于从人类到病毒的各种系统。研究结果包括发现鱼类中意外的生殖不平等,对历史上鲸鱼数量的新估计,史前野牛数量减少的人类免责,以及对人类Y染色体选择性扫描的推断。本文综述了现有的家谱采样器软件,包括数据要求和每个程序使用的限制。
Coalescent genealogy samplers attempt to estimate past qualities of a population, such as its size, growth rate, patterns of gene flow or time of divergence from another population, based on samples of molecular data. Genealogy samplers are increasingly popular because of their potential to disentangle complex population histories. In the last decade they have been widely applied to systems ranging from humans to viruses. Findings include detection of unexpected reproductive inequality in fish, new estimates of historical whale abundance, exoneration of humans for the prehistoric decline of bison and inference of a selective sweep on the human Y chromosome. This review summarizes available genealogy-sampler software, including data requirements and limitations on the use of each program.