Validity and reliability of aortic pulse wave velocity and augmentation index determined by the new cuff-based SphygmoCor Xcel
Validity and reliability of aortic pulse wave velocity and augmentation index determined by the new cuff-based SphygmoCor Xcel
复制标题
DOI：
10.1038/jhh.2013.144
复制
发表时间：
2014-08-01
影响因子：
2.7
通讯作者：
Christou, D. D.
中科院分区：
文献类型：
--
作者：
Hwang, M-H;Yoo, J-K;Christou, D. D.
主动脉脉搏波速度（AoPWV）和增强指数（AIx）分别是大弹性动脉硬度和波反射的常用指标。最近，已经开发了一种新的基于袖带的SphygmoCor设备（Xcel）来测量AoPWV和AIx。我们试图检查以下内容：（1）Xcel与经过充分验证的基于眼压测量的SphygmoCor设备（MM 3）相比的有效性;（2）Xcel的测试内和日常可靠性;（3）身体侧（右侧或左侧）对Xcel测量值的影响;以及（4）Xcel测量值与颈动脉顺应性、扩张性和β硬度指数的关系。我们发现Xcel和MM 3之间的AoPWV和AIx测量值没有差异（分别为P = 0.26和P = 0.43，N = 22和26），并且具有强相关性（r = 0.85和0.75，P < 0.0001），并且基于Bland-Altman图，它们之间具有良好的一致性。组内相关性（组内相关性= 0.996和0.983，P < 0.0001; AoPWV和AIx，N = 24和26）和日常可靠性（组内相关性= 0.979和0.939，P < 0.0001）较高。Xcel AoPWV和AIx在左与右体侧无差异（分别为P = 0.19和P = 0.58，N = 14和15），并且高度相关（r = 0.99和0.94，P < 0.0001）。AoPWV和AIx与b-僵硬指数呈正相关（r = 0.62和0.51，P
Aortic pulse wave velocity (AoPWV) and augmentation index (AIx) are commonly used measures of large elastic artery stiffness and wave reflection, respectively. Recently, a new cuff-based SphygmoCor device (Xcel) has been developed to measure both AoPWV and AIx. We sought to examine the following: (1) the validity of Xcel compared with the well-validated tonometry-based SphygmoCor device (MM3); (2) the intratest and day-to-day reliability of Xcel; (3) the influence of body side (right or left) on Xcel measurements; and (4) the relation of Xcel measurements to carotid artery compliance, distensibility and beta-stiffness index. We found that measurements of AoPWV and AIx between Xcel and MM3 were not different (P = 0.26 and P = 0.43, N = 22 and 26, respectively) and were strongly related (r = 0.85 and 0.75, P < 0.0001), and based on Bland-Altman plots there was good agreement between them. Intra-test (intraclass correlation = 0.996 and 0.983, P < 0.0001; AoPWV and AIx, N = 24 and 26, respectively) and day-to-day reliability (intraclass correlation = 0.979 and 0.939, P < 0.0001) were high. Xcel AoPWV and AIx on the left versus right body side were not different (P = 0.19 and P = 0.58, N = 14 and 15, respectively) and were highly correlated (r = 0.99 and 0.94, P < 0.0001). AoPWV and AIx measured with Xcel were positively related with b-stiffness index (r = 0.62 and 0.51, P