Magnetic Resonance Elastography of Liver: Current Update.
Magnetic Resonance Elastography of Liver: Current Update.
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DOI：
10.1097/rmr.0000000000000177
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发表时间：
2018-10
期刊：
影响因子：
--
通讯作者：
Venkatesh SK
中科院分区：
文献类型：
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作者：
Hoodeshenas S;Yin M;Venkatesh SK
磁共振弹性成像(MRE)首次临床应用于慢性肝病(CLD)的检测和肝纤维化分期。在过去的十年里，MRE已经无缝地纳入了全球标准的MRI肝脏方案。肝脏MRE是一种可靠的评估肝脏硬度的技术，也是目前评估肝纤维化最准确的无创性成像技术。较新的MRE序列，包括自旋回波MRE和三维MRE，有助于减少2DGRE MRE临床肝脏MRE的技术限制。MRE技术的进步使人们了解了新的力学参数，如弥散、衰减和粘弹性，这些参数可能有助于评估慢性肝病的病理过程，并可能被证明对它们的处理有用。本文将介绍引起硬挺度增加的慢性阻塞性肺疾病的改变，并介绍肝脏磁共振成像的原理和技术。在综述的后半部分，我们将简要讨论肝脏MRE的进展。
The first clinical application of magnetic resonance elastography (MRE) was in the evaluation of chronic liver disease (CLD) for detection and staging of liver fibrosis. In the past ten years, MRE has been incorporated seamlessly into a standard MRI liver protocol worldwide. Liver MRE is a robust technique for evaluation of liver stiffness and is currently the most accurate non-invasive imaging technology for evaluation of liver fibrosis. Newer MRE sequences including spin echo MRE and three- dimensional MRE have helped in reducing the technical limitations of clinical liver MRE that is performed with 2D GRE MRE. Advances in MRE technology has led to understanding of newer mechanical parameters such as dispersion, attenuation and viscoelasticity that may be useful in evaluating pathological processes in chronic liver disease and may prove useful in their management. This review article will describe the changes in CLD that cause increase in stiffness followed by principle and technique of liver MRE. In the later part of the review, we will briefly discuss the advances in liver MRE.