A PROSPECTIVE-STUDY OF THE RELATION BETWEEN SMOKING AND FERTILITY
A PROSPECTIVE-STUDY OF THE RELATION BETWEEN SMOKING AND FERTILITY
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DOI：
10.1093/ije/17.2.378
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发表时间：
1988-06-01
影响因子：
7.7
通讯作者：
SCHWARTZ, D
中科院分区：
文献类型：
--
作者：
DEMOUZON, J;SPIRA, A;SCHWARTZ, D
1977年至1982年进行了一项生育率前瞻性研究。本文对1887对夫妇进行了吸烟与妊娠关系的分析。一年结束时的精算妊娠率为82.9%。当单独考虑吸烟因素时，发现夫妻双方都吸烟与生育能力下降有关。但在将所有混杂协变量纳入生存数据的考克斯半比例风险模型后，吸烟与生育之间没有任何关系。女性吸烟和男性吸烟的优势比分别为0.86（95%置信区间：0.63，1.19）和0.99（0.85，1.14）。这可能表明，其他作者发现的关系可能至少部分地由吸烟和其他与生育有关的因素之间的关系来解释。
A prospective study of fertility was conducted from 1977 to 1982. Analysis of the relation between cigarette smoking and occurrence of a pregnancy was performed on 1887 couples. The actuarial pregnancy rate was 82.9% at the end of a year. Cigarette smoking by both members of the couple was found to be related to decreased fertility when this factorwas considered alone. But after including all the confounding covariates in a Cox semi-proportional hazards model for survival data, no relationship remained between cigarette smoking and fertility. Odds ratios were respectively 0.86 (95% confidence interval: 0.63, 1.19) and 0.99 (0.85, 1.14) for women smoking and men smoking. This could suggest that the relationship found by other authors might be at least partly explained by a relation between cigarette smoking and other factors related to fertility.