Knee injury and Osteoarthritis Outcome Score (KOOS) - validation and comparison to the WOMAC in total knee replacement.
Knee injury and Osteoarthritis Outcome Score (KOOS) - validation and comparison to the WOMAC in total knee replacement.
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DOI：
10.1186/1477-7525-1-17
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发表时间：
2003-05-25
影响因子：
3.6
通讯作者：
Toksvig-Larsen, Soren
中科院分区：
文献类型：
--
作者：
Roos, Ewa M;Toksvig-Larsen, Soren
背景技术背景：膝关节损伤和骨关节炎结局评分（KOOS）是西安大略和麦克马斯特大学骨关节炎指数（WOMAC）的扩展，WOMAC是评估骨关节炎患者相关治疗效果的最常用结局工具。KOOS是为膝关节损伤和膝关节骨关节炎的年轻和/或更活跃的患者开发的，并且在之前对这些人群的研究中，与WOMAC相比，KOOS是反应更灵敏的工具。一些符合全膝关节置换术条件的患者期望获得比日常生活所需更苛刻的身体功能。这鼓励我们研究使用膝关节损伤和骨关节炎结局评分（KOOS），以评估全膝关节置换术的结果。方法：我们研究了瑞典版本LK 1.0的KOOS的重测信度，有效性和反应性时，用于前瞻性地评估105例患者（平均年龄71.3，66名妇女）全膝关节置换术后的结果。随访率在6个月和12个月分别为92%和86%，results.Results：组内相关系数均超过0.75的所有分量表表示足够的重测信度。Bland-Altman图证实了这一发现。超过90%的患者认为在决定进行膝关节手术时，疼痛、症状、日常生活活动和膝关节相关生活质量子量表的改善非常重要或非常重要，表明内容效度良好。与SF-36相比发现的相关性表明KOOS测量了预期结构。反应最快的子量表是膝关节相关生活质量。12个月时KOOS 5个分量表的效应量范围为1.08 ~ 3.54，WOMAC的效应量范围为1.65 ~ 2.56。结论：膝关节损伤和骨关节炎结局评分（KOOS）是一种有效、可靠、反应灵敏的全关节置换术结局指标。与WOMAC相比，KOOS提高了有效性，并且可能至少与WOMAC一样具有响应性。
BACKGROUND: The Knee injury and Osteoarthritis Outcome Score (KOOS) is an extension of the Western Ontario and McMaster Universities Osteoarthrtis Index (WOMAC), the most commonly used outcome instrument for assessment of patient-relevant treatment effects in osteoarthritis. KOOS was developed for younger and/or more active patients with knee injury and knee osteoarthritis and has in previous studies on these groups been the more responsive instrument compared to the WOMAC. Some patients eligible for total knee replacement have expectations of more demanding physical functions than required for daily living. This encouraged us to study the use of the Knee injury and Osteoarthritis Outcome Score (KOOS) to assess the outcome of total knee replacement.METHODS: We studied the test-retest reliability, validity and responsiveness of the Swedish version LK 1.0 of the KOOS when used to prospectively evaluate the outcome of 105 patients (mean age 71.3, 66 women) after total knee replacement. The follow-up rates at 6 and 12 months were 92% and 86%, respectively.RESULTS: The intraclass correlation coefficients were over 0.75 for all subscales indicating sufficient test-retest reliability. Bland-Altman plots confirmed this finding. Over 90% of the patients regarded improvement in the subscales Pain, Symptoms, Activities of Daily Living, and knee-related Quality of Life to be extremely or very important when deciding to have their knee operated on indicating good content validity. The correlations found in comparison to the SF-36 indicated the KOOS measured expected constructs. The most responsive subscale was knee-related Quality of Life. The effect sizes of the five KOOS subscales at 12 months ranged from 1.08 to 3.54 and for the WOMAC from 1.65 to 2.56.CONCLUSION: The Knee injury and Osteoarthritis Outcome Score (KOOS) is a valid, reliable, and responsive outcome measure in total joint replacement. In comparison to the WOMAC, the KOOS improved validity and may be at least as responsive as the WOMAC.