Soil ecotoxicity of polycyclic aromatic hydrocarbons in relation to soil sorption, lipophilicity, and water solubility
Soil ecotoxicity of polycyclic aromatic hydrocarbons in relation to soil sorption, lipophilicity, and water solubility
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DOI：
10.1021/es010180s
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发表时间：
2002-06-01
影响因子：
11.4
通讯作者：
Krogh, PH
中科院分区：
文献类型：
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作者：
Sverdrup, LE;Nielsen, T;Krogh, PH
生成的数据集，旨在预测多环芳烃对土壤生物的毒性。毒性数据包括16多环芳烃的生存和繁殖的土壤居住的跳虫Folsomia fimetaria的影响。结果表明，只有报告的log K-ow值小于或等于5.2（即，萘、苊、苊烯、蒽、菲、芴、芘和荧蒽）显着影响测试生物的生存或繁殖。单个多环芳烃的毒性阈值可以表示为孔隙水浓度通过使用报告的有机碳归一化土壤孔隙水分配系数（K-OC值）。对于log K-ow +/- 5.2的多环芳烃，毒性随着物质亲脂性的增加而显著增加（r（2）= 0.67; p 0.012; n = 8），表明大多数物质的毒性作用为麻醉模式。然而，蒽在回归图中的位置表明毒性作用模式比麻醉更特异，去除该数据点得到以下回归方程：log EC 10（mumol/L）= -0.97 log K-ow + 4.0（r（2）= 0.80; p = 0.006; n 7）。利用这种定量构效关系（QSAR）计算剩余无毒物质的毒性阈值（苯并[a]蒽、蒽、苯并[B]荧蒽、苯并[k]荧蒽、二苯并[a，h]蒽、苯并[a]芘、二萘嵌苯和茚并[1，2，3-cd]芘），在大多数情况下，无毒性可解释为水溶性有限，这表明这些物质确实通过麻醉作为毒性作用的模式而起作用，并且它们的毒性取决于孔隙水中的浓度。研究结果提供了重要的投入，未来的模型预测多环芳烃污染场地所造成的生态风险。
A data set was generated aiming to predict the toxicity of PAHs to soil organisms. Toxicity data include the effects of 16 PAHs on the survival and reproduction of the soil-dwelling springtail Folsomia fimetaria. The results show that only PAHs with reported log K-ow values less than or equal to 5.2 (i.e., naphthalene, acenaphthene, acenaphthylene, anthracene, phenanthrene, fluorene, pyrene, and fluoranthene) significantly affected the survival or reproduction of the test organisms. Threshold values for the toxicity of the individual PAHs could be expressed as pore-water concentrations by the use of reported organic carbon-normalized soil-pore-water partitioning coefficients (K-oc values). For the PAHs with a log K-ow +/- 5.2, toxicity significantly increased with increasing lipophilicity of the substances (r(2) = 0.67; p 0.012; n = 8), suggesting a narcotic mode of toxic action for most substances. However, the position of anthracene in the regression plot indicated a more specific mode of toxic action than narcosis, and removing this data point yielded the following regression equation: log EC10 (mumol/L) = -0.97 log K-ow + 4.0 (r(2) = 0.80; p = 0.006; n 7). Using this quantitative structure-activity relationship (QSAR) to calculate threshold values for the toxicity of the remaining nontoxic substances (benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, dibenz[a,h]anthracene, benzo[a]pyrene, perylene, and indeno[1,2,3-cd]pyrene), the absence of toxicity could in most cases, be explained by a limited water solubility, indicating that these substances do act by narcosis as the mode of toxic action and that their toxicity is governed by concentrations in the pore-water. The results provide important input to future model predictions of the ecological risk posed by PAH contaminated sites.