White Paper on CTSA Consortium Role in Facilitating Comparative Effectiveness Research

White Paper on CTSA Consortium Role in Facilitating Comparative Effectiveness Research
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DOI:
10.1111/j.1752-8062.2010.00177.x
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发表时间:
2010-02-01
影响因子:
3.9
通讯作者:
Whitlock, Evelyn P.
Whitlock, Evelyn P.
中科院分区:
医学3区
文献类型:
--
作者:
Selker, Harry P.;Strom, Brian L.;Whitlock, Evelyn P.

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2006年,美国国立卫生研究院(NIH)发起了临床和转化科学奖(CTSAs),作为NIH路线图倡议的一部分,以改善NIH的临床和转化研究组合的行为和影响。CTSA计划的目的不仅是改变个别学术机构的培训计划和研究基础设施,而且要创建一个全国性的合作联盟来改变生物医学研究企业。2009年1月,美国国立卫生研究院CTSA国家联盟通过了战略目标,以最大限度地发挥CTSA对国家医疗保健和健康的影响。其中,CTSA战略目标4是促进临床和转化研究成果转化为实践和公共政策。为了推进这一目标,成立了一个委员会,重点组织和发展CTSA联盟的比较反思研究(CER)能力,这是研究转化为实践和政策的一个日益重要的组成部分。该委员会的工作组为实现这一目标承担了许多可交付成果,包括为NIH的研究所和中心(ic)、其他联邦机构、外部利益相关者和整个医疗保健系统编写关于CTSA联盟如何最好地促进CER的白皮书。本白皮书为CTSA联盟如何支持这一新兴的、至关重要的国家努力提供了一些具体建议,以产生、综合和传播CER,以改善医疗保健决策和健康结果。
In 2006, the National Institutes of Health (NIH) initiated the Clinical and Translational Science Awards (CTSAs) as part of the NIH Roadmap Initiative, in order to improve the conduct and impact of NIH's clinical and translational research portfolio. 1 The CTSA program is intended not only to transform the training programs and research infrastructure at individual academic institutions, but also to create a nation‐wide collaborative consortium to transform the biomedical research enterprise. In January 2009, the NIH CTSA National Consortium adopted Strategic Goals to maximize the CTSAs’ impact on the Nation's healthcare and health. Of these, the CTSA Strategic Goal 4 is to promote the translation of the results of clinical and translational research into practice and public policy. To advance this goal, a committee was constituted to focus on the organization and development of the CTSA Consortium's comparative eflEctiveness research (CER) capacity, an increasingly important component of research translation into practice and policy. This Committee's Workgroups took on a number of deliverables in service of this objective, including producing this White Paper on how the CTSA Consortium might best facilitate CER, for NIH's Institutes and Centers (ICs), other Federal agencies, outside stakeholders, and the healthcare system overall. This White Paper offers some specific suggestions for how the CTSA Consortium might support this emerging and crucial national effort to generate, synthesize, and disseminate CER in order to improve healthcare decision‐making and health outcomes.