Changes in urine volume and serum albumin in incident hemodialysis patients
Changes in urine volume and serum albumin in incident hemodialysis patients
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DOI：
10.1111/hdi.12517
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发表时间：
2017-10-01
影响因子：
1.3
通讯作者：
Kalantar-Zadeh, Kamyar
中科院分区：
文献类型：
--
作者：
Eriguchi, Rieko;Obi, Yoshitsugu;Kalantar-Zadeh, Kamyar
Introduction: Hypoalbuminemia is a predictor of poor outcomes in dialysis patients. Among hemodialysis patients, there has not been prior study of whether residual kidney function or decline over time impacts serum albumin levels. We hypothesized that a decline in residual kidney function is associated with an increase in serum albumin levels among incident hemodialysis patients.Methods: In a large national cohort of 38,504 patients who initiated hemodialysis during 1/2007-12/2011, we examined the association of residual kidney function, ascertained by urine volume and renal urea clearance, with changes in serum albumin over five years across strata of baseline residual kidney function, race, and diabetes using case-mix adjusted linear mixed effects models.Findings: Serum albumin levels increased over time. At baseline, patients with greater urine volume had higher serum albumin levels: 3.44 +/- 0.48, 3.50 +/- 0.46, 3.57 +/- 0.44, 3.59 +/- 0.45, and 3.65 +/- 0.46 g/dL for urine volume groups of
