Intraluminal brachytherapy using the high dose rate microSelectron in the palliation of carcinoma of the oesophagus.
Intraluminal brachytherapy using the high dose rate microSelectron in the palliation of carcinoma of the oesophagus.
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DOI：
10.1016/s0936-6555(05)80810-6
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发表时间：
1995-01-01
期刊：
影响因子：
--
通讯作者：
Burt, P A
中科院分区：
文献类型：
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作者：
Brewster, A E;Davidson, S E;Burt, P A
在1988年6月至1992年6月期间，共有197例晚期食管癌患者在克里斯蒂医院接受了高剂量率微选择治疗。在54%的患者中，单次腔内近距离治疗导致了有效的缓解，这种缓解持续了患者剩余生命的大部分时间。治疗的简单性，可以作为一天的病例程序完成，不会引起显著的发病率，在缓解这些总体生存和生活质量差的患者方面值得称赞。讨论了可能提高那些在单次治疗后没有获得显著缓解的患者的反应率的方法。
A total of 197 patients, who presented to the Christie Hospital with advanced carcinoma of the oesophagus, were treated with the high dose rate microSelectron between June 1988 and June 1992. In 54%, a single intraluminal brachytherapy treatment resulted in useful palliation, which was sustained for a substantial part of the patient's remaining life. The simplicity of the treatment, which could be completed as a day case procedure and did not cause significant morbidity, commends itself in the palliation of these patients who have poor overall survival and quality of life. Approaches that might improve the response rate in those patients who did not gain significant palliation after a single treatment are discussed.