THE INFLUENCE OF ELEVATED LEVELS OF SODIUM IN DRINKING-WATER ON ELEMENTARY AND HIGH-SCHOOL-STUDENTS IN MASSACHUSETTS
THE INFLUENCE OF ELEVATED LEVELS OF SODIUM IN DRINKING-WATER ON ELEMENTARY AND HIGH-SCHOOL-STUDENTS IN MASSACHUSETTS
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DOI：
10.1016/s0048-9697(81)80054-x
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发表时间：
1981-01-01
影响因子：
9.8
通讯作者：
TUTHILL, RW
中科院分区：
文献类型：
--
作者：
CALABRESE, EJ;TUTHILL, RW
马萨诸塞州大学持续进行的流行病学研究已经检验了饮用水中钠（Na）水平升高导致血压（BP）升高的假设。比较十年级学生从一个城镇与107毫克钠/升的饮用水，从一个城镇与8毫克，钠/升，显示统计学显着和医学上重要的高血压分布之间的高钠镇学生相对于他们的低钠镇同龄人的收缩压和舒张压的男孩和女孩。当潜在的混杂因素，包括膳食钠摄入量和其他水因素发生差异，在两种供水，在分析中得到控制时，差异得到维持。在同一社区的三年级学生中进行的一项重复研究显示了类似的结果。最近，一项实验性瓶装水研究评估了降低高钠社区四年级学生水中钠浓度对血压的影响。在三个月的时间里，三组按性别、学校和基线血压匹配的儿童在所有烹饪和饮用目的中都使用不同的水，每两周监测一次血压。学生被随机分配到三种水条件下：1）从自己的社区分配系统瓶装的高钠水，2）从比较社区的分配系统瓶装的低钠水，其中钠被添加到高钠社区水的水平，以及3）从低钠社区的配水系统樽装但不加钠的低钠水。初步结果显示，与其他两组相比，低钠水组的女孩在测试期间血压明显下降。
Continuing epidemiologic studies at the University of Massachusetts have examined the hypothesis that elevated levels of sodium (Na) in drinking water contribute to elevations of blood pressure (BP). Comparing tenth graders from a town with 107 mg Na/L in the drinking water to those from a town with 8 mg, Na/L, revealed statistically significant and medically important higher BP distributions among the high Na town students relative to their low Na town peers for both systolic and diastolic BP in both boys and girls. The differences were upheld when potentially confounding factors, including dietary Na intake and other water factors occurring differentially in the two water supplies, were controlled in the analysis. A replication study among third graders in the same communities showed similar results.Most recently, an experimental bottled water study assessed the effect on bloodpressure of lowering Na concentration in the water of some of the high sodium community fourth graders. For three months trios of children matched by sex, school, and baseline BP each used different water for all cooking and drinking purposes, with BP monitored bi-weekly. Pupils were randomly allocated to the three water conditions: 1) high sodium water bottled from their own community distribution system, 2) low sodium water bottled from the distribution system of the comparison community with sodium added to the level of the high sodium community water and 3) low sodium water bottled from the distribution system of the low sodium community but with no sodium added.Preliminary results indicate the BP levels of the girls on the low sodium waterexhibited marked decreases in BP over the test period when compared to the other two groups.