Admixture and diversity in West African cattle populations
Admixture and diversity in West African cattle populations
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DOI：
10.1111/j.1365-294x.2004.02311.x
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发表时间：
2004-11-01
影响因子：
4.9
通讯作者：
Bradley, DG
中科院分区：
文献类型：
--
作者：
Freeman, AR;Meghen, CM;Bradley, DG
我们提出了一个群体遗传分析的微卫星变异在16个西非牛种群。西非在一个相对较小的地理区域内，是不同气候和生态区并存的独特地区。虽然较潮湿的沿海地区居住着采采蝇，这是一种在牛中传播锥虫病的媒介，但这种疾病不会在该地区以外的干燥地区传播。这是对该地区牛的遗传多样性最彻底的研究，其中包含遗传上重要的抗锥虫牛品种。研究了许多品种之间的遗传关系，并评估了多样性水平。使用多种方法测定混合物水平。使用来自印度、近东和欧洲的人群选择遗传学信息或人群相关等位基因（PAA）。多元分析，ADMIX程序和基于模型的贝叶斯混合分析方法也被采用。这些分析揭示了生态因素的直接影响和该地区的牛的混合物的深刻影响。他们还强调了努力防止非洲牛磺酸品种被B进一步稀释的重要性。印度牛
We present a population genetic analysis of microsatellite variation in 16 West African cattle populations. West Africa represents a unique juxtaposition of different climatic and ecological zones in a relatively small geographical area. While more humid coastal regions are inhabited by the tsetse fly, a vector which spreads trypanosomiasis among cattle, the disease is not transmitted in the drier areas outside this zone. This is the most thorough study of genetic diversity in cattle within this area, which contains genetically important trypanotolerant Bos taurus breeds. Genetic relationships among the many breeds are examined and levels of diversity are assessed. Admixture levels were determined using a variety of methods. Ancestry informative or population-associated alleles (PAAs) were selected using populations from India, the Near East and Europe. Multivariate analysis, the ADMIX program and model-based Bayesian admixture analysis approaches were also employed. These analyses reveal the direct impact of ecological factors and the profound effect of admixture on the cattle of this region. They also highlight the importance of efforts to prevent further dilution of African taurine breeds by B. indicus cattle.