Comorbid Psychiatric Disorders Associated with Asperger Syndrome/High-functioning Autism: A Community- and Clinic-based Study
Comorbid Psychiatric Disorders Associated with Asperger Syndrome/High-functioning Autism: A Community- and Clinic-based Study
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DOI：
10.1007/s10803-010-0958-2
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发表时间：
2010-09-01
影响因子：
3.9
通讯作者：
Moilanen, Irma
中科院分区：
文献类型：
--
作者：
Mattila, Marja-Leena;Hurtig, Tuula;Moilanen, Irma
本研究采用学龄儿童情感障碍和精神分裂症量表（现版和终身版），在社区和诊所样本中确定了50名9- 16岁受试者中与Alfreger综合征（AS）/高功能自闭症（HFA）相关的共病精神障碍的患病率和类型。使用儿童总体评估量表评估功能水平。结果支持AS/HFA中常见（患病率74%）且经常是多种共病的精神疾病;行为障碍占44%，焦虑障碍占42%，抽动障碍占26%。对立违抗性障碍、重性抑郁障碍和焦虑障碍作为共病条件表明功能水平显著降低。针对干预措施，强调对AS/HFA受试者的精神共病进行常规评估。
The present study identifies the prevalence and types of comorbid psychiatric disorders associated with Asperger syndrome (AS)/high-functioning autism (HFA) in a combined community- and clinic-based sample of fifty 9- to 16-year-old subjects using the Schedule for Affective Disorders and Schizophrenia for School-Age Children, Present and Lifetime Version. The level of functioning was estimated using the Children's Global Assessment Scale. The results support common (prevalence 74%) and often multiple comorbid psychiatric disorders in AS/HFA; behavioral disorders were shown in 44%, anxiety disorders in 42% and tic disorders in 26%. Oppositional defiant disorder, major depressive disorder and anxiety disorders as comorbid conditions indicated significantly lower levels of functioning. To target interventions, routine evaluation of psychiatric comorbidity in subjects with AS/HFA is emphasized.