DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets
DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets
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DOI：
10.1093/molbev/msx248
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发表时间：
2017-12-01
影响因子：
10.7
通讯作者：
Sanchez-Gracia, Alejandro
中科院分区：
文献类型：
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作者：
Rozas, Julio;Ferrer-Mata, Albert;Sanchez-Gracia, Alejandro
我们提出了第6版的DNA序列多态性（DnaSP）软件，一个新版本的流行的工具进行详尽的人口遗传分析多序列比对。这一重大升级整合了分析大型数据集的新功能，例如高通量测序技术生成的数据集。除其他功能外，DnaSP 6实现了：1）用于阅读和分析基因组分区方法（如RADseq或杂交富集方法）数据的模块，2）可扩展用于高通量测序数据的更快方法，以及3）用于分析多位点群体遗传学数据的汇总统计。此外，DnaSP 6还包括新颖的模块，可在各种人口统计场景下执行单位点和多位点合并模拟。DnaSP 6程序和大量文档可在http://www.ub.edu/dnasp上免费获得。
We present version 6 of the DNA Sequence Polymorphism (DnaSP) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments. This major upgrade incorporates novel functionalities to analyze large data sets, such as those generated by high-throughput sequencing technologies. Among other features, DnaSP 6 implements: 1) modules for reading and analyzing data from genomic partitioning methods, such as RADseq or hybrid enrichment approaches, 2) faster methods scalable for high-throughput sequencing data, and 3) summary statistics for the analysis of multi-locus population genetics data. Furthermore, DnaSP 6 includes novel modules to perform single- and multi-locus coalescent simulations under a wide range of demographic scenarios. The DnaSP 6 program, with extensive documentation, is freely available at http://www.ub.edu/dnasp.