Can microbiota research change our understanding of neurodegenerative diseases?

Can microbiota research change our understanding of neurodegenerative diseases?
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DOI:
10.2217/nmt-2015-0012
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发表时间:
2016-04
影响因子:
2.6
通讯作者:
F. Scheperjans
F. Scheperjans
中科院分区:
--
文献类型:
--
作者:
F. Scheperjans

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然而,经过几十年的深入研究,我们甚至还没有接近回答最难以捉摸的,也可能是最重要的问题,即“是什么引发了导致进行性神经变性的病理级联反应?”在与这些毁灭性疾病的殊死战斗中,我们应该对那些不受先前方法影响的理论持开放态度,而是从新的角度审视问题。“在与这些毁灭性疾病的绝望斗争中,我们应该对那些不受以前方法影响的理论持开放态度,而是从新的角度审视问题。
However, after decades of intensive research we are not even close to answer the most elusive, and probably most important question of all, namely “What initiates the pathological cascade that leads to progressive neurodegeneration?” In the desperate battle against these devastating disorders we should be open for theories that are free of the legacy of previous approaches, but instead examine the problem from a new perspective. “In the desperate battle against these devastating disorders we should be open for theories that are free of the legacy of previous approaches, but instead examine the problem from a new perspective.”