(+)- and (-)-Spongiterpene, a pair of new valerenane sesquiterpene enantiomers from the marine sponge Spongia Sp.
(+)- and (-)-Spongiterpene, a pair of new valerenane sesquiterpene enantiomers from the marine sponge Spongia Sp.
复制标题
( )- 和 (-)-Spongiterpene，一对来自海洋海绵 Spongia Sp. 的新戊烯倍半萜对映体。
DOI：
10.1080/14786419.2019.1666384
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发表时间：
2019-09-19
影响因子：
2.2
通讯作者：
Xu, Shi-Hai
中科院分区：
文献类型：
--
作者：
Liang, Yong-Qian;Liao, Xiao-Jian;Xu, Shi-Hai
从海绵Spongia sp.中分离得到一对新的戊烯烷型倍半萜对映体（（+）-和（-）-海绵萜[（+）-1和（-）-1]，沿着4个已知化合物（2-5）。化合物（+）-1和（-）-1是首次从海绵中分离得到的戊烯烷型倍半萜。还评价了（+）-1和（-）-1的细胞毒活性。
(+)- and (-)-Spongiterpene [(+)-1 and (-)-1], a pair of new valerenane sesquiterpene enantiomers, along with four known compounds (2-5) were isolated from the marine sponge Spongia sp. The structures of (+)-1 and (-)-1 including absolute configurations were determined by spectroscopic analysis, quantum chemical calculation and X-ray diffraction. Compounds (+)-1 and (-)-1 were the first examples of valerenane sesquiterpenes isolated from the marine sponges. The cytotoxic activities of (+)-1 and (-)-1 were also evaluated.