CENTRILOBULAR LESIONS OF THE LUNG - DEMONSTRATION BY HIGH-RESOLUTION CT AND PATHOLOGICAL CORRELATION
CENTRILOBULAR LESIONS OF THE LUNG - DEMONSTRATION BY HIGH-RESOLUTION CT AND PATHOLOGICAL CORRELATION
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DOI：
10.1148/radiology.161.3.3786710
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发表时间：
1986-12-01
期刊：
影响因子：
19.7
通讯作者：
TORIZUKA, K
中科院分区：
文献类型：
--
作者：
MURATA, K;ITOH, H;TORIZUKA, K
为探讨高分辨率CT（HRCT）在弥漫性肺部疾病诊断中的价值，对4个充气固定的尸检肺标本进行了HRCT与病理对照研究。在正常肺中，通过HRCT分辨的最小肺动脉直径为200 μ m;该动脉伴有终末细支气管和一级呼吸性细支气管。从血管到相应小叶边缘的距离范围为3 ~ 5 mm。这些结果表明，小叶中心区或终末或呼吸性细支气管周围的区域可以通过HRCT识别。此外，作者证实，小叶中心型肺气肿和小叶中心型结核性结节可通过HRCT诊断。因此，HRCT可以显示病变在小叶内的位置，并有助于弥漫性肺疾病的鉴别诊断。
To determine the value of high-resolution computed tomography (HRCT) in the diagnosis of diffuse pulmonary diseases, a direct HRCT-pathologic correlative study was performed using four inflated and fixed lungs from autopsy. In normal lungs, the smallest pulmonary artery resolved by HRCT was 200 .mu.m in diameter; the artery was accompanied by the terminal bronchiole and the first-order respiratory bronchiole. The distance from the vessel to the corresponding lobular border ranged from 3 to 5 mm. These results suggest that the centrilobular area or the area around the terminal or respiratory bronchioles can be recognized with HRCT. In addition, the authors confirmed that centrilobular emphysema and centrilobular tuberculous nodules can be diagnosed with HRCT. Thus, HRCT can demonstrate the location of pathologic changes within a lobule and may be helpful in the differential diagnosis of diffuse pulmonary diseases.