CHEMOTAXIS BY NEMATODE CAENORHABDITIS-ELEGANS - IDENTIFICATION OF ATTRACTANTS AND ANALYSIS OF RESPONSE BY USE OF MUTANTS
CHEMOTAXIS BY NEMATODE CAENORHABDITIS-ELEGANS - IDENTIFICATION OF ATTRACTANTS AND ANALYSIS OF RESPONSE BY USE OF MUTANTS
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DOI：
10.1073/pnas.70.3.817
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发表时间：
1973-01-01
影响因子：
11.1
通讯作者：
WARD, S
中科院分区：
文献类型：
--
作者：
WARD, S
秀丽隐杆线虫至少被四类引诱剂吸引：环核苷酸，cAMP和cGMP;阴离子，Cl-，Br-，I-;阳离子，Na+，Li+，K+，Mg+;和碱性pH值。线虫对这些引诱剂梯度的行为反应包括定向和沿梯度向上移动、积累，然后习惯化。野生型和突变体动物响应梯度的引诱剂的轨道的比较表明，在头部的感觉受体单独介导的方向响应和方向是由头部的横向运动。因此，定向反应是一种趋性。
The nematodeCaenorhabditis elegansis attracted by at least four classes of attractants: by cyclic nucleotides, cAMP and cGMP; by anions, Cl-, Br-, I-; by cations, Na+, Li+, K+, Mg+; and by alkaline pH values. The nematode's behavioral response to gradients of these attractants involves orientation and movement up the gradient, accumulation, and then habitutation. Comparison of the tracks of wild-type and mutant animals responding to gradients of attractants indicates that sensory receptors in the head alone mediate the orientation response and that the direction of orientation is determined by the lateral motion of the head. Therefore, the orientation response is a klinotaxis.