Fungal keratitis caused by Colletotrichum gloeosporioides
Fungal keratitis caused by Colletotrichum gloeosporioides
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DOI：
10.1097/00003226-200111000-00027
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发表时间：
2001-11-01
期刊：
影响因子：
2.8
通讯作者：
Ishibashi, Y
中科院分区：
文献类型：
--
作者：
Yamamoto, N;Matsumoto, T;Ishibashi, Y
目的。描述一例由一种罕见的空腔菌病原菌炭疽菌引起的真菌性角膜炎。方法。一位82岁的骨髓增生异常综合征患者在左眼白内障手术6个月后发生真菌性角膜炎。由于开始使用纳他霉素后前房的检查结果恶化，因此开始使用局部和全身氟康唑进行额外治疗。结果。角膜刮伤分离株生长有gloeosporioides。抗真菌治疗2个月后，角膜病变消失，5年随访无感染复发。结论。纳他霉素与氟康唑联合治疗gloeosporioides是有效的。
Purpose. To describe a case of fungal keratitis caused by a rare coelomycete pathogen, Colletotrichum gloeosporioides. Methods. An 82-year-old man with myelodysplastic syndrome developed fungal keratitis 6 months after cataract surgery in the left eye. Because the findings of the anterior chamber deteriorated after the initiation of natamycin, additional treatment with topical and systemic fluconazole was initiated. Results. The isolates of corneal scraping grew C. gloeosporioides. After antifungal treatment of 2 months, the corneal lesion resolved with no recurrence of infection over a 5-year follow-up period. Conclusions. A combination treatment of natamycin and fluconazole was effective in the treatment of C. gloeosporioides.