Electrochemical chiral recognition of tryptophan using a glassy carbon electrode modified with β-cyclodextrin and graphene
Electrochemical chiral recognition of tryptophan using a glassy carbon electrode modified with β-cyclodextrin and graphene
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DOI：
10.1007/s00604-014-1174-0
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发表时间：
2014-04-01
影响因子：
5.7
通讯作者：
Nan, Junmin
中科院分区：
文献类型：
--
作者：
Feng, Wanlian;Liu, Chao;Nan, Junmin
我们报告了一种色氨酸（Trp）对映体的电化学对映选择性识别方法。它基于与石墨烯纳米片结合的脱氧-(2-氨基乙基氨基)-β-环糊精 (CD) 和色氨酸对映体的 Cu(II) 复合物之间通过配体交换机制的竞争性主客体相互作用。通过循环伏安法和电化学阻抗谱研究手性识别。结果表明，与石墨烯结合的 CD 与 L-Trp 的 Cu(II) 络合物的相互作用比与 D-Trp 的相互作用更强。该方法适用于测定混合物中色氨酸对映体的比例。
We report on a method for electrochemical enantioselective recognition of tryptophan (Trp) enantiomers. It is based on competitive host-guest interaction between a deoxy-(2-aminoethylamino)-beta-cyclodextrin (CD) bound to graphene nanosheets and the Cu(II) complexes of the Trp enantiomers via a ligand exchange mechanism. Chiral recognition was investigated via cyclic voltammetry and electrochemical impedance spectroscopy. The results reveal that the CD bound to graphene displays a stronger interaction with the Cu(II) complex of L-Trp than to that of D-Trp. The method was applied to the determination of the ratio of Trp enantiomers in mixtures.