Upper abdominal normal organ contouring guidelines and atlas: a Radiation Therapy Oncology Group consensus.

Upper abdominal normal organ contouring guidelines and atlas: a Radiation Therapy Oncology Group consensus.
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DOI:
10.1016/j.prro.2013.06.004
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发表时间:
2014-03
影响因子:
3.3
通讯作者:
Dawson, Laura A
Dawson, Laura A
中科院分区:
医学3区
文献类型:
--
作者:
Jabbour, Salma K;Hashem, Sameh A;Bosch, Walter;Kim, Tae Kyoung;Finkelstein, Steven E;Anderson, Bethany M;Ben-Josef, Edgar;Crane, Christopher H;Goodman, Karyn A;Haddock, Michael G;Herman, Joseph M;Hong, Theodore S;Kachnic, Lisa A;Mamon, Harvey J;Pantarotto, Jason R;Dawson, Laura A

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标准化放射治疗肿瘤组(RTOG)试验的上腹部正常器官轮廓勾画指南。12名放射肿瘤专家勾画了肝脏、食管、胃食管交界处(GEJ)、胃、十二指肠和胆总管(CBD)的轮廓,并在匿名患者计算机断层扫描(CT)数据集上审查和编辑了33个额外的正常器官和血管轮廓。使用MATLAB(MathWorks,Natick,MA)覆盖轮廓并比较一致性。生成S95轮廓(定义为二项分布,以生成95%组一致轮廓)和正常器官轮廓定义,并由专家组进行审查。使用Kappa统计量,肝脏、十二指肠和胃轮廓具有极好的一致性和一致性,食管轮廓具有实质性一致性,GEJ和CBD轮廓具有中等一致性。共识的定义,详细的正常器官轮廓的建议和高分辨率的图像。共识轮廓指引和CT图像图谱应改善放射肿瘤学临床规划和RTOG试验中轮廓的一致性。
To standardize upper abdominal normal organ contouring guidelines for Radiation Therapy Oncology Group (RTOG) trials. Twelve expert radiation oncologists contoured the liver, esophagus, gastroesophageal junction (GEJ), stomach, duodenum, and common bile duct (CBD), and reviewed and edited 33 additional normal organ and blood vessel contours on an anonymized patient computed tomography (CT) dataset. Contours were overlaid and compared for agreement using MATLAB (MathWorks, Natick, MA). S95 contours, defined as the binomial distribution to generate 95% group consensus contours, and normal organ contouring definitions were generated and reviewed by the panel. There was excellent consistency and agreement of the liver, duodenal, and stomach contours, with substantial consistency for the esophagus contour, and moderate consistency for the GEJ and CBD contours using a Kappa statistic. Consensus definitions, detailed normal organ contouring recommendations and high-resolution images were developed. Consensus contouring guidelines and a CT image atlas should improve contouring uniformity in radiation oncology clinical planning and RTOG trials.