Cognitive enhancement by transcranial laser stimulation and acute aerobic exercise
Cognitive enhancement by transcranial laser stimulation and acute aerobic exercise
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DOI：
10.1007/s10103-016-1962-3
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发表时间：
2016-08-01
影响因子：
2.1
通讯作者：
Gonzalez-Lima, F.
中科院分区：
文献类型：
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作者：
Hwang, Jungyun;Castelli, Darla M.;Gonzalez-Lima, F.
这是第一项比较经颅激光刺激和急性有氧运动对相同认知任务的认知影响的随机对照研究。我们研究了经颅红外激光刺激前额叶皮层、急性高强度有氧运动或两者结合是否可以提高持续注意力和工作记忆任务的表现。60名健康青年被随机分配到以下四种治疗之一：（1）低强度激光治疗（LLLT），在坐位时用红外激光照射两个前额部位（共8分钟，1064 nm连续波，250 mW/cm（2），60 J/cm（2）/13.6 cm（2）部位）;（2）高强度急性运动（EX）（总共20分钟，在85- 90%VO（2）max下跑10分钟）;（3）联合治疗（LLLT + EX）;或（4）假对照（CON）。参与者在治疗前后分别用心理警觉任务（PVT）和延迟匹配样本任务（DMS）测试前额叶持续注意力和工作记忆。与CON相比，LLLT和EX都减少了PVT中的反应时间[F（1.56）= 4.134，p = 0.01，eta（2）= 0.181]，并增加了DMS中的正确反应数[F（1.56）= 4.690，p = 0.005，eta（2）= 0.201]，表明LLLT和EX对认知表现的显著增强作用。LLLT + EX的效果相似，但对PVT和DMS的改善并不比LLLT或EX单独使用更显著。经颅红外激光刺激和急性有氧运动治疗对认知增强同样有效，这表明它们类似地增强了前额叶认知功能。
This is the first randomized, controlled study comparing the cognitive effects of transcranial laser stimulation and acute aerobic exercise on the same cognitive tasks. We examined whether transcranial infrared laser stimulation of the prefrontal cortex, acute high-intensity aerobic exercise, or the combination may enhance performance in sustained attention and working memory tasks. Sixty healthy young adults were randomly assigned to one of the following four treatments: (1) low-level laser therapy (LLLT) with infrared laser to two forehead sites while seated (total 8 min, 1064 nm continuous wave, 250 mW/cm(2), 60 J/cm(2) per site of 13.6 cm(2)); (2) acute exercise (EX) of high-intensity (total 20 min, with 10-min treadmill running at 85-90 % VO(2)max); (3) combined treatment (LLLT + EX); or (4) sham control (CON). Participants were tested for prefrontal measures of sustained attention with the psychomotor vigilance task (PVT) and working memory with the delayed match-to-sample task (DMS) before and after the treatments. As compared to CON, both LLLT and EX reduced reaction time in the PVT [F(1.56) = 4.134, p = 0.01, eta (2) = 0.181] and increased the number of correct responses in the DMS [F(1.56) = 4.690, p = 0.005, eta (2) = 0.201], demonstrating a significant enhancing effect of LLLT and EX on cognitive performance. LLLT + EX effects were similar but showed no significantly greater improvement on PVT and DMS than LLLT or EX alone. The transcranial infrared laser stimulation and acute aerobic exercise treatments were similarly effective for cognitive enhancement, suggesting that they augment prefrontal cognitive functions similarly.