Electrochemical Synthesis of 2-Hydroxy-para-terphenyls by Dehydrogenative Anodic C–C Cross-Coupling Reaction
Electrochemical Synthesis of 2-Hydroxy-para-terphenyls by Dehydrogenative Anodic C–C Cross-Coupling Reaction
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DOI：
10.1055/s-0037-1611942
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发表时间：
2019-01
期刊：
影响因子：
2
通讯作者：
S. Lips;R. Franke;S. Waldvogel
中科院分区：
文献类型：
--
作者：
S. Lips;R. Franke;S. Waldvogel
摘要阳极C-C交叉偶联反应提供了通过电化学介导的芳基化反应快速获得广泛的双和三元支架的途径。本文首次提出了一种无金属、无试剂的非对称2-羟基对四芳基衍生物的电合成方法。它是可扩展的，易于进行，并允许使用各种不同的官能团。
Abstract The anodic C–C cross-coupling reaction provides fast access to a wide range of bi- and terarylic scaffolds by electrochemically mediated arylation reactions. Herein, a metal- and reagent-free electrosynthetic protocol for the synthesis of nonsymmetrical 2-hydroxy-para-teraryl derivatives is presented for the first time. It is scalable, easy to conduct, and allows the use of a broad variety of different functional groups.