Preparation of polylactic acid composites containing β–Ca(PO_3)_2 fibers
Preparation of polylactic acid composites containing β–Ca(PO_3)_2 fibers
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含β-Ca(PO_3)_2纤维的聚乳酸复合材料的制备
DOI：
10.1557/jmr.1999.0060
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发表时间：
1999
影响因子：
2.7
通讯作者：
Y. Abe
中科院分区：
文献类型：
--
作者：
T. Kasuga;H. Fujikawa;Y. Abe
以生物可吸收材料L乳酸和稀碱处理的高强度β-Ca(PO3)2纤维为原料，制备了弹性模数接近天然骨的新型人工骨生物材料。将用二氯甲烷溶解的PLLA与纤维混合。将混合物干燥后，在40 Mpa、180℃的压力下进行单轴热压，制得含β-Ca(PO3)2纤维的聚乳酸复合材料。当纤维用量较大(≈50wt.%)时，弯曲强度几乎没有下降，弹性模数随纤维含量的增加而有效提高。当纤维含量超过35wt%时，可制得弹性模数接近于天然骨的PLLA复合材料。弯曲试验表明，复合材料的断裂耗能很高，而且断裂是逐步进行的，甚至超过了最大应力。
Novel biomaterials for application to artificial bone with modulus of elasticity close to that of natural bone were prepared using bioresorbable poly-L-lactic acid (PLLA) and high-strength β–Ca(PO_3)_2 fibers treated with dilute NaOH solution. PLLA dissolved by using methylene chloride was mixed with the fibers. After drying the mixture, it was hot-pressed uniaxially under a pressure of 40 MPa at 180 °C, resulting in fabrication of a PLLA composite containing β–Ca(PO_3)_2 fibers. Almost no degradation in the bending strength was observed even when a large amount of the fibers (≈50 wt. %) was introduced, and the modulus of elasticity was increased effectively with increasing the fiber content. The PLLA composite with modulus of elasticity of <5 GPa similar to that of natural bone was found to be prepared when the fiber content was over 35 wt. %. The bending test of the composites showed that very high energy is consumed for their fracture and that the fracture proceeds step by step, even beyond the maximum stress.