Age-specific salivary immunoglobulin A response to Streptococcus mutans GbpB.
Age-specific salivary immunoglobulin A response to Streptococcus mutans GbpB.
复制标题
年龄特异性唾液免疫球蛋白 A 对变形链球菌 GbpB 的反应。
DOI：
10.1128/cvi.00098-07
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
Mattos-Graner,RenataO
中科院分区：
文献类型：
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作者：
Nogueira,RucheleD;Alves,AlessandraC;King,WilliamF;Goncalves,ReginaldoB;Hofling,JoseF;Smith,DanielJ;Mattos-Graner,RenataO
在一项对早期感染变形链球菌的儿童的随访研究中（先前显示儿童对toS反应较差）。mutansGbpB)，他们的免疫反应是延迟的，而不是完全不能对这种抗原作出反应。GbpB n端三分之一的表位被确定为早期儿童自然诱导的免疫球蛋白A抗体的靶点。
In a follow-up study of children infected withStreptococcus mutansat an early age (children previously shown to respond poorly toS. mutansGbpB), there was a delay in their immune response, rather than a complete inability to respond to this antigen. Epitopes in the N-terminal third of GbpB were identified as targets for naturally induced immunoglobulin A antibody in children at an early age.