EFFECTS OF COLLAGEN ORIENTATION ON MR-IMAGING CHARACTERISTICS OF BOVINE ARTICULAR-CARTILAGE
EFFECTS OF COLLAGEN ORIENTATION ON MR-IMAGING CHARACTERISTICS OF BOVINE ARTICULAR-CARTILAGE
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DOI：
10.1148/radiology.188.1.8511302
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发表时间：
1993-07-01
期刊：
影响因子：
19.7
通讯作者：
HENKELMAN, RM
中科院分区：
文献类型：
--
作者：
RUBENSTEIN, JD;KIM, JK;HENKELMAN, RM
为了确定胶原取向对关节软骨磁共振成像表现的影响，在+75度和-130度之间以5度的增量旋转正常牛膝骨标本，获得了自旋回波MR图像。浅层为高信号，中部为低信号，深板为中等信号。组织学标本的偏光显微镜结果证实了这三个区，而透射电子显微镜显示这三个区的胶原排列不同。旋转对信号强度的各向异性影响明显，特别是在低信号的第二椎板。由于与胶原相关的水分子优先排列，软骨沿最小偶极耦合方向(与磁场成55度角)的角度旋转使软骨具有均匀的外观。这些层的磁共振成像外观受到胶原纤维的各向异性排列以及样品相对于磁场的排列的强烈影响。
To determine the influence of collagen orientation on the magnetic resonance (MR) imaging appearance of articular cartilage, spin-echo MR images of normal bovine patellar specimens were obtained with the specimen rotated in 5-degrees increments between +75-degrees and -130-degrees. Hyperintense superficial, hypointense middle, and intermediate-intensity deep laminae were observed. Results of polarized light microscopy of histologic specimens confirmed the three zones, and transmission electron microscopy showed different collagen arrangements in the zones. An anisotropic effect of rotation on signal intensity was evident especially in the hypointense second lamina. Because of the preferential alignment of water molecules associated with collagen, angular rotation of the cartilage in the direction of minimum dipolar coupling (55-degrees to the magnetic field) caused the cartilage to have a homogeneous appearance. The MR imaging appearance of these layers is strongly influenced by an anisotropic arrangement of the collagen fibers and by the alignment of the specimen relative to the magnetic field.