Functional associations among trauma, PTSD, and substance-related disorders

Functional associations among trauma, PTSD, and substance-related disorders
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DOI:
10.1016/s0306-4603(98)00070-7
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发表时间:
1998-11-01
影响因子:
4.4
通讯作者:
Dongier, M
Dongier, M
中科院分区:
医学2区
文献类型:
--
作者:
Stewart, SH;Pihl, RO;Dongier, M

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这篇综述文章提出了几个潜在的功能途径,可以解释创伤后应激障碍和物质滥用障碍在创伤个体中的频繁共同发生。新兴的实证研究已经审查了这些潜在的途径,包括研究相对顺序的发病,PTSD患者的看法,各种药物的影响,比较PTSD患者与无共病物质使用障碍,和相关性研究检查之间的关系,具体的PTSD症状群和物质障碍症状的严重程度。回顾了酒精和其他药物对与PTSD侵入和唤醒症状相关的认知和生理变量的急性和慢性影响的研究,以突出这两组PTSD症状可能与药物滥用在功能上相关的方式。最后,基于这些发现,提出了治疗PTSD-物质使用障碍共病个体的建议。(C)1998 Elsevier Science Ltd.
This review article presents several potential functional pathways which may explain the frequent co-occurrence of PTSD and substance abuse disorders in traumatized individuals. Emerging empirical studies which have examined these potential pathways are reviewed, including studies on relative order of onset, PTSD patients' perceptions of various drug effects, comparisons of PTSD patients with and without comorbid substance use disorders, and correlational studies examining the relations between severity of specific PTSD symptom clusters and substance disorder symptoms. Research on the acute and chronic effects of alcohol and other drugs on cognitive and physiological variables relevant to PTSD intrusion and arousal symptoms is reviewed to highlight ways in which these two sets of PTSD symptoms might be functionally interrelated with substance abuse. Finally, based on these findings, recommendations are made for the treatment of individuals with comorbid PTSD-substance use disorders. (C) 1998 Elsevier Science Ltd.