STRUCTURAL PLASTICITY IN THE DROSOPHILA BRAIN
STRUCTURAL PLASTICITY IN THE DROSOPHILA BRAIN
复制标题
DOI：
10.1523/jneurosci.15-03-01951.1995
复制
发表时间：
1995-03-01
影响因子：
5.3
通讯作者：
WANKE, C
中科院分区：
文献类型：
--
作者：
HEISENBERG, M;HEUSIPP, M;WANKE, C
果蝇的大脑大小变化很大。在人口稠密的幼虫培养中生长的雌性果蝇的蘑菇体中的凯尼恩细胞纤维比低密度培养的果蝇多20%。凯尼恩细胞纤维数量的差异伴随着花萼体积的差异。在想象生活中，在肾盏、视叶的所有部分、中央脑和中央复合体中观察到体积变化。它们不仅发生在成年的第一周，而且发生在第8天至第16天之间。引起这些变化的因素知之甚少。在成对饲养1周的果蝇中，花萼的大小而不是小叶的大小受到伴侣性别的影响。女性有更大的花萼，如果合作伙伴是女性比如果它是男性。男性似乎也受到同样的影响。在其想象生活的第一周，孤独地生活在小食物小瓶中的雌性比在人口密集的飞行笼中度过一周的雌性具有更小的小叶。40只动物组成的异性恋群体的雄性和雌性的小叶、髓质和肾盏仍然比单独饲养的兄弟姐妹小。此外，大脑的大小还受到尚未确定的因素的影响，这些因素导致了长期和短期的趋势。这些数据表明，在果蝇中，大脑的大多数神经元区域在整个生命过程中不断重组，以应对特定的生活条件。
The Drosophila brain is highly variable in size. Female flies grown in densely populated larval cultures have up to 20% more Kenyon cell fibers in their mushroom bodies than flies from low-density cultures. These differences in the number of Kenyon cell fibers are accompanied by differences in the volume of the calyx. During imaginal life, volume changes are observed in the calyces, all parts of the optic lobes, the central brain, and central complex. They occur not only in the first week of adulthood but also between days 8 and 16. Factors causing these changes are little understood. In flies kept in pairs for 1 week, the size of the calyx but not of the lobula is influenced by the sex of the partner. Females have larger calyces if the partner is female than if it is male. Males seem to be affected in the same way. Females living solitarily in little food vials for the first week of their imaginal life have smaller lobulae than females having spent the week in a populated flight cage. Males and females of heterosexual groups of 40 animals have still smaller lobulae, medullae, and calyces than their siblings kept in isolation. In addition, brain size is influenced by yet unidentified factors causing long and short trends. The data suggest that in Drosophila, most neuropil regions of the brain are continuously reorganized throughout life in response to specific living conditions.