Approaches for assessing olfaction in children with autism spectrum disorders.

Approaches for assessing olfaction in children with autism spectrum disorders.
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评估患有自闭症谱系障碍的儿童的嗅觉的方法。

DOI:
10.1007/978-1-4939-8609-5_16
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发表时间:
2018
期刊:
Mehods in Molecular Biology.
影响因子:
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通讯作者:
Kikuchi M.
Kikuchi M.
中科院分区:
--
文献类型:
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作者:
Kumazaki H;Okamoto M;Kanzaki S;Okada K;Mimura M;Minabe Y;Kikuchi M.

文献摘要

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自闭症谱系障碍(ASD)患者的嗅觉特征被认为是社交障碍的最强预测因子。与其他感觉异常相比,ASD患者的嗅觉异常知之甚少。在这一章中,我们提供了一个目前的评估与ASD个人的概述。在对ASD患者的嗅觉进行研究时,必须考虑几个混杂因素。嗅觉的定性测量仅包含关于嗅觉刺激的有限信息。此外,关于个人在日常生活中实际使用嗅觉的系统信息很少。只有有限数量的实验研究进行了定量测量的嗅觉异常的ASD。因此,在实验室环境中澄清嗅觉特征和现实生活中的影响之间的关系是非常困难的。一些新的测量嗅觉特征的方法正逐渐成为可能。新的方法,揭示ASD和嗅觉性状之间的重要联系,应在未来开发。
Olfactory traits in individuals with autism spectrum disorder (ASD) are considered the strongest predictors of social impairment. Compared to other sensory abnormalities, olfactory abnormalities in individuals with ASD are poorly understood. In this chapter, we provide an overview of the current assessment in individuals with ASD. Several confounding factors have to be considered when conducting research on olfaction in individuals with ASD. Qualitative measures of olfaction contain only limited information about the olfactory stimuli. In addition, little systematic information is available about individual’s actual uses of olfaction in daily life. Only a limited number of experimental studies have performed quantitative measurements of olfactory abnormalities in ASD. Therefore, clarifying the relationship between olfactory traits and the influence of real-life situations in a laboratory setting is very difficult. Some new methodologies for measuring olfactory traits are gradually becoming available. New methods that reveal important links between ASD and olfactory traits should be developed in the future.