Intestinal transport of manganese from human milk, bovine milk and infant formula in rats.
Intestinal transport of manganese from human milk, bovine milk and infant formula in rats.
复制标题
大鼠体内母乳、牛乳和婴儿配方奶粉中锰的肠道转运。
DOI：
10.1016/0024-3205(84)90449-1
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发表时间：
1984
期刊：
影响因子：
6.1
通讯作者：
Torres-Pinedo,R
中科院分区：
文献类型：
--
作者：
Chan,WY;BatesJr,JM;Rennert,OM;Mahmood,A;Torres-Pinedo,R
采用膨出肠囊法研究了外标人乳、牛乳和婴幼儿配方奶粉中锰的转运。组织/粘膜通量数据表明，与人乳相比，牛奶和配方奶向肠道组织中的锰转运显著增加。同样，当使用母乳时，锰从粘膜到浆膜表面的总通量较少。与高分子量的锰结合配体相比，从牛奶样品中分离出的小分子量锰结合配体增强了锰的粘膜到组织的运动。最重要的是，数据表明，在母乳及其分离的锰组分中，锰的运输和吸收比在牛奶或婴儿配方奶粉中要少。
The transport of manganese from extrinsically labeled human milk, bovine milk and infant formula was studied by the everted intestinal sac method. Tissue/mucosal flux data indicated that transport of manganese into the intestinal tissue was significantly greater with bovine milk and formula than from human milk. Similarly, the total flux of manganese from the mucosal to serosal surface was less when human milk was used. Smaller molecualr weight manganese binding ligands isolated from the milk samples enhanced the mucosal to tissue movement of manganese as contrasted to the higher molecular weight manganese binding ligands. Most significantly the data suggest that the transport and uptake of manganese is less in the presence of human milk and its isolated manganese fractions than it is in bovine milk or infant formula.