Management of Elevated Intraocular Pressure Associated With Subluxated/Dislocated Lenses by Combining Trabeculectomy With Adjunctive Mitomycin C With Lensectomy, Vitrectomy, and Scleral Fixation of Intraocular Lens
Management of Elevated Intraocular Pressure Associated With Subluxated/Dislocated Lenses by Combining Trabeculectomy With Adjunctive Mitomycin C With Lensectomy, Vitrectomy, and Scleral Fixation of Intraocular Lens
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DOI：
10.1097/ijg.0000000000000344
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发表时间：
2016-07-01
影响因子：
2
通讯作者：
Lingam, Vijaya
中科院分区：
文献类型：
--
作者：
David, Rathini L.;Balekudaru, Shantha;Lingam, Vijaya
目的：评价晶状体切除术联合玻璃体切除术、巩膜固定人工透镜（SFIOL）和小梁切除术联合应用丝裂霉素C（MMC）治疗晶状体半脱位/脱位伴眼内压（IOP）升高患者的短期疗效。材料和方法：该回顾性病例系列包括51例患者的51只眼，这些患者接受了晶状体切除术，玻璃体切除术，2003年至2012年，SFIOL联合小梁切除术和MMC。评估的主要结局指标为IOP、视力变化、降IOP药物、并发症和再手术率。结果：观察到的最常见病因为钝伤35眼（68.6%）。术前发现青光眼性视神经病变13眼（25.49%）。最终访视时，IOP从术前平均值26.3 ± 11.5 mm Hg显著降低至13 ± 4.6 mm Hg（P < 0.001）。术前降眼压药物的平均数量为2.9 ± 0.8，末次随访时降至0.3 ± 0.7（P < 0.001）。最佳矫正视力（Snellens）由术前的20/600提高到术后的20/60（P < 0.001）。完全成功定义为IOP
Aim: To evaluate the short-term outcomes of lensectomy, combined with vitrectomy, scleral-fixated intraocular lens (SFIOL), and trabeculectomy with adjunctive mitomycin C (MMC) in patients with subluxated/dislocated crystalline lenses with associated elevated intraocular pressure (IOP).Materials and Methods: This retrospective case series included 51 eyes of 51 patients who underwent lensectomy, vitrectomy, and SFIOL combined with trabeculectomy with MMC between 2003 and 2012. The main outcome measures assessed were IOP, change in visual acuity, IOP-lowering medications, and the complications and reoperation rates.Results: The most common etiology observed was blunt trauma in 35 eyes (68.6%). Glaucomatous optic neuropathy was detected in 13 eyes (25.49%) preoperatively. The IOP reduced significantly from a preoperative mean of 26.3 +/- 11.5 mm Hg to 13 +/- 4.6 mm Hg (P < 0.001) at the final visit. The mean preoperative number of IOP-lowering medications of 2.9 +/- 0.8 reduced to 0.3 +/- 0.7 at last follow-up (P < 0.001). The best-corrected visual acuity (Snellens) improved significantly from 20/600 to 20/60 (P < 0.001). Complete success defined as IOP