AMYGDALA CENTRAL NUCLEUS LESIONS DISRUPT INCREMENTS, BUT NOT DECREMENTS, IN CONDITIONED-STIMULUS PROCESSING
AMYGDALA CENTRAL NUCLEUS LESIONS DISRUPT INCREMENTS, BUT NOT DECREMENTS, IN CONDITIONED-STIMULUS PROCESSING
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DOI：
10.1037/0735-7044.107.2.246
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发表时间：
1993-04-01
影响因子：
1.9
通讯作者：
GALLAGHER, M
中科院分区：
文献类型：
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作者：
HOLLAND, PC;GALLAGHER, M
在大鼠的两个实验中，观察了杏仁中央核(CN)神经毒性损毁对食欲巴甫洛夫条件反射条件刺激(CS)关联性改变的影响。在实验1中，CN损毁对因预先暴露于该线索(潜在抑制)而产生的CS的关联性降低没有影响。在实验2中，CN损伤阻止了CS关联性的增强，而这种增强通常是在CS和另一条线索之间安排了不一致的预测关系时观察到的。这一结果支持了之前的说法，即杏仁核参与了巴甫洛夫条件反射处理过程中广泛的递增但不是递减的变化。
The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexposure to that cue (latent inhibition). In Experiment 2, CN lesions prevented the enhancement of the associability of a CS that is normally observed when an inconsistent predictive relation is arranged between that CS and another cue. The results support previous claims that the amygdala CN is involved in broad-based incremental, but not decremental, changes in the processing of CSs in Pavlovian conditioning.