Proteoglycans and Glycosaminoglycans in Stem Cell Homeostasis and Bone Tissue Regeneration.
Proteoglycans and Glycosaminoglycans in Stem Cell Homeostasis and Bone Tissue Regeneration.
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干细胞稳态和骨组织再生中的蛋白聚糖和糖胺聚糖
DOI:
10.3389/fcell.2021.760532
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发表时间:
2021
影响因子:
5.5
通讯作者:
Wu J
中科院分区:
文献类型:
--
作者:
Chen J;Sun T;You Y;Wu B;Wang X;Wu J
Stem cells maintain a subtle balance between self-renewal and differentiation under the regulatory network supported by both intracellular and extracellular components. Proteoglycans are large glycoproteins present abundantly on the cell surface and in the extracellular matrix where they play pivotal roles in facilitating signaling transduction and maintaining stem cell homeostasis. In this review, we outline distinct proteoglycans profiles and their functions in the regulation of stem cell homeostasis, as well as recent progress and prospects of utilizing proteoglycans/glycosaminoglycans as a novel glycomics carrier or bio-active molecules in bone regeneration.
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影响因子:
7.8
作者:
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通讯作者:
Emerson, Charles P Jr
影响因子:
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影响因子:
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通讯作者:
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影响因子:
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作者:
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通讯作者:
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