A case of collagenofibrotic glomerulopathy associated with hepatic perisinusoidal fibrosis.
A case of collagenofibrotic glomerulopathy associated with hepatic perisinusoidal fibrosis.
复制标题
与肝窦周纤维化相关的胶原纤维性肾小球病一例。
作者：
S. Mizuiri;A. Hasegawa;A. Kikuchi;Y. Amagasaki;N. Nakamura;H. Sakaguchi
一个病人胶原纤维性肾小球病与肝肝纤维化是描述。肾活检显示肾小球束含有均匀物质，经电镜证实为胶原纤维。该材料对抗ⅲ型胶原单克隆抗体有反应。肝活检也显示肝窦周围III型胶原纤维增多。由于该患者血清III型前胶原肽水平升高，肾脏和肝脏的纤维化可能在某种未知情况下同时被激活。
A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibody. Liver biopsy also showed an increase of type III collagen fibers in the perisinusoidal area. Since the serum procollagen III peptide level was elevated in this patient, fibrosis may have been simultaneously activated in kidney and liver by some unknown condition.