Adult Supraglottitis: A Prospective Analysis
Adult Supraglottitis: A Prospective Analysis
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成人声门上炎：前瞻性分析
DOI：
10.1001/jama.1988.03720040055027
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
A. Baker
中科院分区：
文献类型：
--
作者：
J. Shapiro;R. Eavey;A. Baker
儿科患者的会厌炎是由 b 型流感嗜血杆菌引起的感染，可迅速导致败血症和窒息死亡。为了研究成人会厌炎的病因和临床病程，对十个月内连续住院的八名声门上炎成人患者进行了前瞻性评估，包括每日喉部检查。尽管喉部和口咽部的多个解剖部位发炎，但会厌通常不是受累最严重的区域，并且在一名患者中实际上是正常的。从所有患者的血液、鼻咽、口咽和会谷以及两名患者的会厌前间隙中收集细菌培养物。在任何情况下均未发现流感嗜血杆菌。没有患者出现呼吸困难。结论是，会厌炎是对这种疾病的不准确描述，并且这种非流感嗜血杆菌成人种类的声门上炎似乎比传统描述的感染的危害性要小。 （美国医学会杂志 1988；259：563-567）
Epiglottitis in pediatric patients is an infection caused by Haemophilus influenzae type b, which can lead rapidly to sepsis and an asphyxial death. In an effort to study the cause and clinical course of adult epiglottitis, eight serially hospitalized adult patients with supraglottitis over a ten-month period were prospectively evaluated, including a daily laryngeal examination. Although multiple anatomic sites in the larynx and oropharynx were inflamed, the epiglottis was often not the most involved area and was actually normal in one patient. Bacterial cultures were harvested from blood, the nasopharynx, the oropharynx, and the vallecula in all patients and the preepiglottic space in two patients. In no case was H influenzae demonstrated. No patient developed respiratory compromise. It was concluded that epiglottitis is an inaccurate description of this disorder and that this non— H influenzae adult variety of supraglottitis seemingly can follow a less pernicious course than the classically described infection. ( JAMA 1988;259:563-567)