Effect of Waon Therapy on Oxidative Stress in Chronic Heart Failure
Effect of Waon Therapy on Oxidative Stress in Chronic Heart Failure
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DOI：
10.1253/circj.cj-10-0630
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发表时间：
2011-02-01
影响因子：
3.3
通讯作者：
Tei, Chuwa
中科院分区：
文献类型：
--
作者：
Fujita, Shoji;Ikeda, Yoshiyuki;Tei, Chuwa
背景：我们团队之前的一份报告显示，使用60摄氏度远红外线干桑拿的Waon疗法可以改善慢性心力衰竭（CHF）患者的心脏和血管功能。本研究旨在通过动物实验阐明Waon治疗对CHF患者氧化应激的影响，并探讨其作用机制。方法与结果：40例CHF患者分为对照组（n=20）和Waon治疗组（n=20）。所有患者均接受标准的最佳CHF药物治疗。Waon治疗组每日给予Waon治疗，连续4周。Waon治疗4周后，过氧化氢和脑利钠肽（BNP）浓度显著降低（过氧化氢，422 +/- 116至327 +/- 88）
Background: A previous report by our team showed that Waon therapy, using a far infrared-ray dry sauna at 60 degrees C, improves cardiac and vascular function in patients with chronic heart failure (CHF). The purpose of the present study was to clarify the effect of Waon therapy on oxidative stress in CHF patients and investigate its mechanism by animal experiments.Methods and Results: Forty patients with CHF were divided into control (n=20) and Waon therapy (n=20) groups. All patients received standard optimal medications for CHF. Waon therapy group was treated with Waon therapy daily for 4 weeks. After 4 weeks of Waon therapy, concentrations of hydroperoxide and brain natriuretic peptide (BNP) decreased significantly (hydroperoxide, 422 +/- 116 to 327 +/- 88 U.CARR, P