Percutaneous transluminal coronary angioplasty in African-American patients (the National Heart, Lung, and Blood Institute 1985-1986 Percutaneous Transluminal Coronary Angioplasty Registry).
Percutaneous transluminal coronary angioplasty in African-American patients (the National Heart, Lung, and Blood Institute 1985-1986 Percutaneous Transluminal Coronary Angioplasty Registry).
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非裔美国患者的经皮腔内冠状动脉成形术（国家心肺血液研究所 1985-1986 经皮腔内冠状动脉成形术登记处）。
DOI：
10.1016/0002-9149(94)90171-6
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
King3rd,SB
中科院分区：
文献类型：
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作者：
Scott,NA;Kelsey,SF;Detre,K;Cowley,M;King3rd,SB
尽管黑人患者冠状动脉疾病的危险因素患病率较高，但黑人患者冠状动脉血管成形术的结果尚不清楚。本研究的目的是确定1985-1986年国家心肺血液研究所(NHLBI)经皮冠状动脉腔内成形术(PTCA)登记的患者的临床特征和结果是否存在种族差异。对1985-1986年NHLBI PTCA登记处登记的所有患者的临床特征、住院事件发生率和5年随访结果进行了种族方面的检查。在登记的患者中，1,939名(90.8%)是白人，76名(3.6%)是黑人。在黑人患者中，有更多的女性(50%对24%，p<；0.001)，以及更多患有高血压(73%对45%，p<；0.001)和糖尿病(23%对13%，p<；0.001)的患者。黑人患者更有可能患有多支血管疾病(72%对48%，p<；0.001)。临床成功率相似(黑人为76.3%，白人为79.3%)，但由于黑人患者有更多有重大疾病的血管，26%的黑人患者实现了完全血管重建，而白人患者的比例为44%(p<；0.001)。PTCA手术后，两组的主要并发症(死亡、心肌梗死或急诊冠状动脉旁路移植术)无显著差异。五年随访数据显示，在死亡率、心肌梗死、冠状动脉旁路移植术或重复PTCA方面没有显著差异。NHLBI PTCA登记中的黑人患者与白人患者相比，尽管存在更多的心血管危险因素、症状和多支血管疾病，但其急性和长期事件的发生率相似。
Although black patients have a higher prevalence of risk factors for coronary artery disease, the outcome of coronary angioplasty in black patients is not known. The purpose of this study was to determine if any racial differences existed in the clinical characteristics and outcome of patients enrolled in the 1985–1986 National Heart, Lung, and Blood Institute (NHLBI) Percutaneous Transluminal Coronary Angioplasty (PTCA) Registry. The clinical characteristics, in-hospital event rates, and 5-year follow-up results of all patients enrolled in the 1985–1986 NHLBI PTCA Registry were examined with respect to race. Of the patients enrolled in the registry, 1,939 (90.8%) were white and 76 (3.6%) were black. Among black patients there were more women (50% vs 24%, p < 0.001), and more patients who had hypertension (73% vs 45%, p < 0.001) and diabetes (23% vs 13%, p < 0.05). Black patients were more likely to have multivessel disease (72% vs 48%, p < 0.001). Clinical success rates were similar (76.3% for blacks and 79.3% for whites), but because black patients had more vessels with significant disease, complete revascularization was achieved in 26% of black patients compared with 44% of white patients (p < 0.001). After the PTCA procedure there was no significant difference in major complications (death, myocardial infarction, or emergent coronary artery bypass grafting) between the 2 groups. Five-year follow-up data revealed that there was no significant difference in mortality, myocardial infarction, coronary artery bypass grafting, or repeat PTCA. Black patients in the NHLBI PTCA Registry had a similar incidence of acute and long-term events when compared with white patients despite the presence of more cardiovascular risk factors, symptoms, and multivessel disease.