Dynamics of infection by leukotoxic strains of Actinobacillus actinomycetemcomitans in juvenile periodontitis.
Dynamics of infection by leukotoxic strains of Actinobacillus actinomycetemcomitans in juvenile periodontitis.
复制标题
幼年牙周炎中伴放线放线杆菌白细胞毒性菌株的感染动态。
DOI：
10.1111/j.1600-051x.1986.tb02231.x
复制
发表时间：
1986
影响因子：
6.7
通讯作者：
Taichman,NS
中科院分区：
文献类型：
--
作者：
Tsai,CC;Taichman,NS
青少年牙周炎与放线杆菌（Aa）感染的高发生率有关。所提供的数据表明，Aa 破坏人类 PMN 的能力在感染过程中发生了改变。 Aa 的白细胞毒性菌株通常存在于年轻患者（6-12 岁）的分离株中，但在老年受试者（13-25 岁）中则没有。这表明白细胞毒素在幼年牙周炎的早期阶段可能比晚期阶段更重要。
Juvenile periodontitis is associated with a high incidence of infection byActinobacillus aclinomycetemcomilans(Aa). The data presented indicate that the ability of Aa to destroy human PMNs is altered during the course of infection. Leukotoxic strains of Aa are characteristically found in isolates obtained from younger patients (6–12 years of age) but not in older subjects (13–25 years old). This suggests that the leukotoxin may be more important during early as opposed to more advanced phases of juvenile periodontitis.